Thymoquinone's Potential Role in Cancer Chemotherapy: A Mini Review

Background: Pollution and genetic factors have increased the likelihood of cancer in developing world. Cancer is now leading cause death young patients. Scientists are focusing on new treatments with a lower risk profile than traditional cytotoxic drugs. Nigella sativa (black seed) has been used for centuries by ancient cultures to treat variety ailments. Thymoquinone, main active compound found sativa, useful therapeutic agent various morbidities, including cancer. Aim: The review aims highlight thymoquinone's potential chemoprotective effects. Methods: most recent articles were using reputable websites such as Google Scholar, PubMed, Research Gate. Many titles, thymoquinone, breast cancer, leukemia, colon osteosarcoma, ovary so on, searches. Then information from vitro studies animal experiments was collected; preprint, article review, meta-analysis study all excluded. Results: Thymoquinone reduced cell viability induced programmed TQ causes cytotoxicity through mechanisms, induction reactive oxygen species inhibition NF-kB activity some cancers. Conclusion: promising future fewer side effects agents.